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Entameba Histolytica

Hussain September 26, 2020

ENTAMEBA HISTOLYTICA 

Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 35-50 million people worldwide. E. histolytica infection is estimated to kill more than 55,000 people each year.


Morphological Forms of Entamoeba Histolytica

1) TROPHOZOITES 

  • Growing, feeding & invading form of E histolytica. 
  • Shape- not fixed due to constantly changing position. 
  • Size 18- 40µm.
  •  Cytoplasm is granular and may contain red cells and having a slow gliding movements due to pseudopodia.

 2) Pre cyst:

  • It is the intermediate stage between trophozoite and cyst
  • It is smaller in size; 10-20µ
  • It is round or slightly ovoid with blunt pseudopodium projecting from periphery
  • No RBC or food materials are found on its endoplasm.

3) Cyst:
  • Infective form of Entameba histolytica. 
  • Rounded shape surrounded by a highly refractile membrane the cyst wall. 
  • Size 10-20µm.
  •  In early stages cytoplasm contain glycogen vacuole & chromotoidal bodies with rounded end that disappear in final quadrinucleate cyst.
  • Non motile and divided by binary fission & develop into binucleate & quadrinucleate bodies.
LIFE CYCLE OF ENTAMEOBA HISTOLYTICA